Sleep-dependent activity of T cells and regulatory T cells

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Sleep-dependent activity of T cells and regulatory T cells.

A number of immunological functions are dependent on circadian rhythms and regular sleep. This has impact on the type and magnitude of immune responses following antigenic challenge, for example in vaccination. Little is known about the underlying mechanisms. One possibility may be the circadian and sleep-dependent modulation of CD4(+)CD25(-) T cell responses by CD4(+)CD25(+) natural regulatory...

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One of the essential protection mechanisms of immune system is Treg cells which play an important role in maintenance ofimmune homeostasis. However, they may also inhibit immune functions against tumor cells. It has been reported that Treg cellsare increased in patients suffering from different types of cancer. Increased number of Treg cells has been shown in tumor lymphnodes, peripheral blood,...

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ژورنال

عنوان ژورنال: Clinical & Experimental Immunology

سال: 2009

ISSN: 0009-9104,1365-2249

DOI: 10.1111/j.1365-2249.2008.03822.x